Therapeutic effects by the peptide drug of p3‐Alcß in AD mouse model

Results suggests that p3-Alcß protects neuronal functions from impairments of brain by revising gene expression profiles which altered by the accumulation of pathogenic and/or denatured proteins in brains. Therefore, the p3-Alcß may be effective as a drug to preserve brain homeostasis from neurodegeneration. Our preclinical observations should light on the clinical trial with the ALC919, the transdermal drug formular of p3-Alcß9-19.