Neuregulin-1 Secreted by Cancer-Associated Fibroblasts Promotes Growth of Triple-Negative Breast Cancer
Our findings suggest that CAF-secreted NRG1 is closely associated with TNBC progression and may represent a potential biomarker and therapeutic target, although further validation is needed to establish causality.
Authors
- Shijie Song (ORCID: https://orcid.org/0000-0002-0219-3841)
- G. Wang
- Yajun Zhang (ORCID: https://orcid.org/0000-0002-1182-6057)
- Lu Xu (ORCID: https://orcid.org/0009-0001-3212-6009)
- Hongbo Xu (ORCID: https://orcid.org/0000-0001-7684-4179)
- Feng Cai
- Dengsheng Jiang
- Xianwen Zhang
- Jing Qian
- Jia Kang
Institutions
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Breast Cancer Targets and Therapy
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/bctt.s549363
- Primary Topic
- HER2/EGFR in Cancer Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00