Reversible Cerebral Vasoconstriction Syndrome Triggered by Whole-Body Cryotherapy in a Teenager

Reversible cerebral vasoconstriction syndrome (RCVS) is uncommon in childhood. Although it usually has favorable outcomes, it still carries a risk of serious complications, including intracranial bleeding and ischemic stroke. RCVS may arise idiopathically, from vasoactive triggers or from daily activities such as defecation, urination, exertion, or sexual activity. Whole-body cryotherapy (WBC) is not officially recognized as a trigger for RCVS. We present a case of RCVS in an adolescent who underwent a WBC session preceding his symptoms and diagnosis. Although an association between cold weather exposure and stroke is recognized, the connection between cold weather and RCVS is less established. Furthermore, there is limited to no evidence linking WBC to stroke or RCVS. We aim to highlight a potential side effect of WBC, an increasingly popular intervention lacking evidence-based benefits and well-studied side effects.

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Publication Details

Journal
Journal of Child Neurology
Published
2025-12-26
DOI
https://doi.org/10.1177/08830738251408116
Primary Topic
Neurological Complications and Syndromes
Type
article
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article

Reversible Cerebral Vasoconstriction Syndrome Triggered by Whole-Body Cryotherapy in a Teenager

Andrea P. Summer, Kasparas Zilinskas, Christina Shen, Marina Dantas
Journal of Child Neurology
Neurological Complications and Syndromes
article

Reversible Cerebral Vasoconstriction Syndrome Triggered by Whole-Body Cryotherapy in a Teenager

Andrea P. Summer, Kasparas Zilinskas, Christina Shen, Marina Dantas
article en

Abstract

Reversible cerebral vasoconstriction syndrome (RCVS) is uncommon in childhood. Although it usually has favorable outcomes, it still carries a risk of serious complications, including intracranial bleeding and ischemic stroke. RCVS may arise idiopathically, from vasoactive triggers or from daily activities such as defecation, urination, exertion, or sexual activity. Whole-body cryotherapy (WBC) is not officially recognized as a trigger for RCVS. We present a case of RCVS in an adolescent who underwent a WBC session preceding his symptoms and diagnosis. Although an association between cold weather exposure and stroke is recognized, the connection between cold weather and RCVS is less established. Furthermore, there is limited to no evidence linking WBC to stroke or RCVS. We aim to highlight a potential side effect of WBC, an increasingly popular intervention lacking evidence-based benefits and well-studied side effects.

Journal of Child Neurology
Children's Mercy Hospital (US), Medical University of South Carolina (US)
Good health and well-being
Openalex Percentile: Top 32%
Neurological Complications and Syndromes
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