Seasonality Patterns in Bipolar Disorder: Associations With Clinical Phenotypes and Treatment‐Related Outcomes

Seasonality in BD is associated with distinct clinical features and treatment-related outcomes. Specific seasonality patterns, particularly fall/winter depression, may reflect a more complex and difficult-to-treat illness course. These findings highlight the need for research to better characterize seasonality subtypes beyond a binary "seasonal" vs. "non-seasonal" classification and to explore how these patterns influence the illness course and management of BD.

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Publication Details

Journal
Acta Psychiatrica Scandinavica
Published
2025-12-26
DOI
https://doi.org/10.1111/acps.70063
Primary Topic
Circadian rhythm and melatonin
Type
article
Field-Weighted Citation Impact
0.00
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article

Seasonality Patterns in Bipolar Disorder: Associations With Clinical Phenotypes and Treatment‐Related Outcomes

Alfredo B Cuéllar Barboza, Brandon J. Coombes, Joanna M. Biernacka, Francisco Romo‐Nava et al.
Acta Psychiatrica Scandinavica
Circadian rhythm and melatonin
article

Seasonality Patterns in Bipolar Disorder: Associations With Clinical Phenotypes and Treatment‐Related Outcomes

Alfredo B Cuéllar Barboza, Brandon J. Coombes, Joanna M. Biernacka, Francisco Romo‐Nava, Mete Ercis, Lindsay Melhuish Beaupre, Ayşegül Özerdem, S L McElroy, Siralp Bostan, Mark A. Frye, Miguel L. Prieto
article en

Abstract

Seasonality in BD is associated with distinct clinical features and treatment-related outcomes. Specific seasonality patterns, particularly fall/winter depression, may reflect a more complex and difficult-to-treat illness course. These findings highlight the need for research to better characterize seasonality subtypes beyond a binary "seasonal" vs. "non-seasonal" classification and to explore how these patterns influence the illness course and management of BD.

Acta Psychiatrica ScandinavicaVol. 153(4)
Ministry of Health (TR), Mayo Clinic (US), Universidad Autónoma de Nuevo León (MX), Universidad de Los Andes, Chile (CL), Lindner Center of HOPE (US), Mayo Clinic in Florida (US), University of Cincinnati Medical Center (US)
Good health and well-being
Openalex Percentile: Top 38%
Circadian rhythm and melatonin
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Seasonality Patterns in Bipolar Disorder: Associations With Clinical Phenotypes and Treatment‐Related Outcomes — Alfredo B Cuéllar Barboza, Brandon J. Coombes, et al. · Acta Psychiatrica Scandinavica (2025) | TGRS Research Map | TGRS