Longitudinal screening and population health strategies for early detection of Alzheimer's disease in Down syndrome

Longitudinal screening before AD symptoms start helps identify earlier AD clinical onset in DS depending on their ID level. Future research should address critical gaps in understanding the heterogeneity of premorbid cognition and key AD outcomes in this population.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70858_106397
Primary Topic
Down syndrome and intellectual disability research
Type
article
Field-Weighted Citation Impact
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article

Longitudinal screening and population health strategies for early detection of Alzheimer's disease in Down syndrome

Bessy Benejam, Lucía Maure‐Blesa, Laura Videla, Isabel Barroeta et al.
Alzheimer s & Dementia
Down syndrome and intellectual disability research
article

Longitudinal screening and population health strategies for early detection of Alzheimer's disease in Down syndrome

Bessy Benejam, Lucía Maure‐Blesa, Laura Videla, Isabel Barroeta, María Carmona‐Iragui, José Enrique Arriola‐Infante, Alexandre Bejanin, Javier Arranz, Juan M. Fortea, Alberto Lleó, Aida Sanjuan Hernandez, Íñigo Rodríguez‐Baz, Susana Fernandez, Lídia Vaqué‐Alcázar, Alejandra O. Morcillo‐Nieto, Laura Del Hoyo
article en

Abstract

Longitudinal screening before AD symptoms start helps identify earlier AD clinical onset in DS depending on their ID level. Future research should address critical gaps in understanding the heterogeneity of premorbid cognition and key AD outcomes in this population.

Alzheimer s & DementiaVol. 21(S4)
Universitat Autònoma de Barcelona (ES), Instituto de Salud Carlos III (ES), Hospital de Sant Pau (ES), Biomedical Research Networking Center on Neurodegenerative Diseases (ES), Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
Openalex Percentile: Top 26%
Down syndrome and intellectual disability research
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