Relationship between Aβ PET Imaging and Cognitive Test Scores in MCI
This study provides valuable insights into the relationship between Aβ PET imaging and cognitive function in both the (CN) and (MCI) subjects. The correlation between SUVr and olfactory function was insignificant. Olfactory measures such as Identification and Threshold may require further improvement to enhance their utility in AD pathophysiology. Overall, our findings show that higher amyloid beta deposition is linked to poorer cognitive performance in MCI. Our results may offer potential avenues to streamline the Neuropsychological test battery for AD by closely tying most salient metrics to amyloid beta deposition.
Authors
- Sangam Kanekar (ORCID: https://orcid.org/0000-0002-4192-7414)
- Paul J. Eslinger (ORCID: https://orcid.org/0000-0002-6032-7801)
- Jens Will
- Prasanna Karunanayaka (ORCID: https://orcid.org/0000-0002-1558-8981)
- Rommy Elyan
- Senal Peiris (ORCID: https://orcid.org/0009-0004-3684-0906)
- Katie Geesey
- Qing Yang
- Anupa Manjitha Ekanayake Mudiyanselage
Institutions
- Pennsylvania State University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_103885
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00