Cerebral Venous Thrombosis in Previously Healthy Patients with Cryptococcal Meningitis

CVST is a potentially treatable complication of CM. MRI and MRV of the brain are valuable diagnostic tools. The absence of thrombophilia mutations suggests that neurologic infection itself contributes to thrombotic risk. Notably, CSF gene expression patterns may serve as biomarkers for CVST susceptibility. Future case-control studies may validate these findings and uncover genetic risk factors contributing to CVST.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2025-12-23
DOI
https://doi.org/10.1093/infdis/jiaf653
Primary Topic
Fungal Infections and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Cerebral Venous Thrombosis in Previously Healthy Patients with Cryptococcal Meningitis

Brittany Dulek, Francisco Otaizo‐Carrasquero, Jessica C. Hargarten, R Ghosh et al.
The Journal of Infectious Diseases
Fungal Infections and Studies
article

Cerebral Venous Thrombosis in Previously Healthy Patients with Cryptococcal Meningitis

Brittany Dulek, Francisco Otaizo‐Carrasquero, Jessica C. Hargarten, R Ghosh, Seher Anjum, Peter R. Williamson, Mari Tokita, Shelley S. Kalsi, Morgan N. Similuk, Andrea Beri, Winnie Trang, Magdelena Walkiewicz-Yvon, Dima A Hammoud
article en

Abstract

CVST is a potentially treatable complication of CM. MRI and MRV of the brain are valuable diagnostic tools. The absence of thrombophilia mutations suggests that neurologic infection itself contributes to thrombotic risk. Notably, CSF gene expression patterns may serve as biomarkers for CVST susceptibility. Future case-control studies may validate these findings and uncover genetic risk factors contributing to CVST.

The Journal of Infectious DiseasesVol. 233(2)
National Institutes of Health (US), National Human Genome Research Institute (US), National Heart, Lung, and Blood Institute (US), National Institute of Allergy and Infectious Diseases (US), National Institutes of Health Clinical Center (US)
Good health and well-being
Openalex Percentile: Top 30%
Fungal Infections and Studies
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