Significance of Enrupatinib, a CSF1R inhibitor, on Decreasing Neuroinflammation and Maintaining Neuronal Health in Mice Models of Alzheimer's Disease
These findings underscore the pharmacological potential of enrupatinib in mitigating Alzheimer's disease-related pathologies. By reducing neuroinflammation and preserving neuronal integrity, enrupatinib offers a promising therapeutic avenue for Alzheimer's disease.
Authors
- Hung‐Kai Chen
- Agnes Dwi Ariyanti
- Wahyu Dewi Tamayanti
- Chia Wei Huang
- J-F Tsai
- Chi Yun Pai
- Haw Yuan Cheng
Institutions
- National Yang Ming Chiao Tung University (TW)
- Elixiron Immunotherapeutics (Taiwan) (TW)
- Institute of Molecular Biology, Academia Sinica (TW)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_102542
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00