Revisiting the Optimal Apparent Diffusion Coefficient Threshold for Ischemic Core Delineation
We revisited the ADC core threshold using a stringent methodology, including EVT-induced ultra-early documented complete recanalization, ≈24-hour follow-up MRI, and EC. The resulting OptADC was marginally smaller than the reference threshold and, accordingly, modestly influenced the measured baseline core volume. The methodological refinements implemented here, including EC, seem essential for future research exploring core ADC.
Authors
- Clément Debacker (ORCID: https://orcid.org/0000-0003-4887-7920)
- Catherine Oppenheim (ORCID: https://orcid.org/0000-0003-3410-0862)
- Clara Cohen (ORCID: https://orcid.org/0000-0002-8200-2784)
- Wagih Ben Hassen (ORCID: https://orcid.org/0000-0003-4858-3623)
- Alice Le Berre
- Joseph Benzakoun
- Jean-Claude Baron
Institutions
- Université d'Orléans (FR)
- Inserm (FR)
- Université Paris Cité (FR)
- Centre Hospitalier Sainte-Anne (FR)
- Institut de Psychiatrie et Neurosciences de Paris (FR)
- Centre hospitalier universitaire d'Orléans (FR)
- FHU Neurovasc (FR)
Publication Details
- Journal
- Neurology
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1212/wnl.0000000000214451
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00