Talin1 modulates the Piezo1–YAP axis to regulate endothelial cell inflammation and atherosclerosis
The results of this study suggest that Talin1 plays a vital role in endothelial inflammation and may be a novel anti-inflammatory therapeutic target for atherosclerosis.
Authors
- Yongmei Nie
- Zhenyu Gao (ORCID: https://orcid.org/0000-0002-4979-2366)
- Haozhong Huang (ORCID: https://orcid.org/0000-0001-7927-9224)
- Zihao Liu (ORCID: https://orcid.org/0009-0002-8037-9630)
- Yan Wang (ORCID: https://orcid.org/0000-0003-2057-0097)
- Fengxu Yu
- Bin Liao
- Yang Long
Institutions
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- First Affiliated Hospital of Sichuan Medical University (CN)
- Ministry of Agriculture (EE)
Publication Details
- Journal
- Cellular and Molecular Life Sciences
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1007/s00018-025-06026-8
- Primary Topic
- Cellular Mechanics and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00