Alzheimer and Neurodegeneration Biomarkers in Mild Cognitive Impairment with Lewy Body Disease in COMPASS‐ND
In COMPASS-ND, participants with features of LB-MCI showed a biomarker profile suggestive of high Alzheimer co-pathology. Higher tau-181 suggests that these individuals might have a higher pathological burden than the other groups. The influence of other co-pathologies (i.e., vascular) and the influence on outcomes will be examined in this cohort. Future studies should examine for the presence of synuclein pathology across these groups.
Authors
- Myrlene Gee (ORCID: https://orcid.org/0000-0001-7934-3695)
- Krista Nelles (ORCID: https://orcid.org/0000-0003-4491-5758)
- Stephen Joza (ORCID: https://orcid.org/0000-0002-5598-4110)
- Eric Edward Smith (ORCID: https://orcid.org/0000-0003-3956-1668)
- Oury Monchi (ORCID: https://orcid.org/0000-0003-2148-5409)
- Richard Camicioli (ORCID: https://orcid.org/0000-0003-2977-8660)
- R. B. Postuma
- Cheryl L. Wellington (ORCID: https://orcid.org/0000-0001-7014-039X)
- Michael Borrie
- Roger A. Dixon
- Mario Masellis
- Desmarais Philippe
- Zahinoor Ismail
- Shady Rahayel
- Howard Chertkow
- Jennifer G Cooper
- Manuel Montero‐Odasso
- Sandra E. Black
- Ging‐Yuek Robin Hsiung
Institutions
- Western University (CA)
- Montreal Neurological Institute and Hospital (CA)
- Lawson Health Research Institute (CA)
- Sunnybrook Health Science Centre (CA)
- University of British Columbia (CA)
- University of Alberta (CA)
- University of Calgary (CA)
- University of Toronto (CA)
- Baycrest Hospital (CA)
- Institut Universitaire de Gériatrie de Montréal (CA)
- Hôpital du Sacré-Cœur de Montréal (CA)
- Centre Hospitalier de l’Université de Montréal (CA)
- Hotchkiss Brain Institute (CA)
- McGill University (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_102379
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00