The Contribution of LATE‐NC to Neuropsychiatric Symptom Burden in Alzheimer's Disease and Lewy Body Disease: A Clinicopathological Study

LATE-NC did not appear to increase overall neuropsychiatric symptom burden in this autopsy cohort study of individuals with AD and/or LBD. Hallucinations were less frequent in the LATE+ group, but this may be due to incomplete adjustment for coexisting Lewy Body pathology. Further modelling of longitudinal symptom progression will be presented at the conference.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_105745
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

The Contribution of LATE‐NC to Neuropsychiatric Symptom Burden in Alzheimer's Disease and Lewy Body Disease: A Clinicopathological Study

Paula Villela Nunes, Ian R. Mackenzie, Imogene Scott, Yara Alkhodair et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

The Contribution of LATE‐NC to Neuropsychiatric Symptom Burden in Alzheimer's Disease and Lewy Body Disease: A Clinicopathological Study

Paula Villela Nunes, Ian R. Mackenzie, Imogene Scott, Yara Alkhodair, Ging‐Yuek Robin Hsiung, Abdulrahman Alzahrani
article en

Abstract

LATE-NC did not appear to increase overall neuropsychiatric symptom burden in this autopsy cohort study of individuals with AD and/or LBD. Hallucinations were less frequent in the LATE+ group, but this may be due to incomplete adjustment for coexisting Lewy Body pathology. Further modelling of longitudinal symptom progression will be presented at the conference.

Alzheimer s & DementiaVol. 21(S3)
Vancouver Coastal Health (CA), University of British Columbia (CA), Positive Living Society of British Columbia (CA)
Quality Education
Openalex Percentile: Top 32%
Dementia and Cognitive Impairment Research
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