Intrinsic and extrinsic risk factors in tumor-related epilepsy
Cortical location, especially in the central lobe, male sex, low BMI and smoking, are independently associated with tumor-related epilepsy. Our findings support the importance of considering both tumor-intrinsic and tumor-extrinsic factors to develop a holistic seizure-risk assessment and highlight the need for larger, prospective studies to refine clinical management and potentially pharmacological seizure prophylaxis.
Authors
- Victor E. Staartjes (ORCID: https://orcid.org/0000-0003-1039-2098)
- Flavio Vasella (ORCID: https://orcid.org/0000-0002-8953-0862)
- Omar Rafi
- N. Krayenbühl
- Stefanos Voglis (ORCID: https://orcid.org/0000-0002-1514-1442)
- K. Akeret
- Carlo Serra (ORCID: https://orcid.org/0000-0002-7305-550X)
- Luca Zanuttini (ORCID: https://orcid.org/0009-0007-6195-1706)
- Luca Regli
- Michael Weller
- Alessandro Carretta
Institutions
- University of Zurich (CH)
- University Hospital of Zurich (CH)
- University Children's Hospital Zurich (CH)
- University of Bologna (IT)
Publication Details
- Journal
- Neurosurgical Review
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1007/s10143-025-04020-z
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00