Mental Health and Brain Morphology: Insights from Long Covid cohort in underrepresented individuals
These preliminary data indicate significant changes in mental health among individuals with Long Covid; however, these changes do not correspond to observable alterations in brain volume as seen in MRI scans. This suggests that the pathophysiological changes associated with these symptoms are likely functional and metabolic in nature rather than structural and may not be detectable through imaging studies that primarily focus on brain anatomy, such as MRI.
Authors
- Tharick Ali Pascoal (ORCID: https://orcid.org/0000-0001-9057-8014)
- Daniele de Paula Faria (ORCID: https://orcid.org/0000-0002-1766-2786)
- Cristina Sebastião Matushita (ORCID: https://orcid.org/0000-0002-7602-0433)
- Luiza Santos Machado (ORCID: https://orcid.org/0000-0001-8387-3832)
- Mychael V. Lourenco (ORCID: https://orcid.org/0000-0002-1078-0296)
- Lucas Uglione Da Ros
- Marco Antônio De Bastiani (ORCID: https://orcid.org/0000-0003-3924-5278)
- Ana Paula Bornes da Silva (ORCID: https://orcid.org/0000-0003-0128-1281)
- Andrei Bieger (ORCID: https://orcid.org/0000-0002-6669-2834)
- Graciane Radaelli (ORCID: https://orcid.org/0000-0002-1208-362X)
- Débora Guerini de Souza (ORCID: https://orcid.org/0000-0003-2982-4989)
- Guilherme Arantes Mello
- João Pedro Uglione da Ros (ORCID: https://orcid.org/0009-0000-1570-0366)
- Joana Emilia Senger
- Arthur Viana Jotz (ORCID: https://orcid.org/0009-0006-5654-0921)
- Matheus Fakhri Kadan
- Maiele Dornelles Silveira
- Artur Francisco Schumacher‐Schuh
- Guilherme Povala
- João Pedro Ferrari‐Souza
- Ricardo Benardi Soder
- Wyllians Vendramini Borelli
- Jaderson Costa da Costa
- Artur Martins Coutinho
- Diogo O. Souza
- Eduardo R. Zimmer
- Pedro Rosa‐Neto
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Universidade Federal do Rio Grande do Sul (BR)
- University of Pittsburgh (US)
- Universidade de São Paulo (BR)
- Instituto do Cérebro (BR)
- Hospital Moinhos de Vento (BR)
- Hospital de Clínicas de Porto Alegre (BR)
- Hospital São Lucas da PUCRS (BR)
- Pontifícia Universidade Católica do Rio Grande do Sul (BR)
- McGill University (CA)
- Universidade Luterana do Brasil (BR)
- University of Gothenburg (SE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_106936
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00