Differences in plasmatic and CSF Alzheimer's Disease biomarkers considering ApoE genotype in mild cognitive impairment and subjective cognitive decline

Plasmatic AD biomarkers did not differ regarding APOE genotype in our sample, but we find a difference in CSF biomarker and the APOE genotype. So, our findings confirm the influence of APOE ε4 allele in central nervous system amyloid levels.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_104334
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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Differences in plasmatic and CSF Alzheimer's Disease biomarkers considering ApoE genotype in mild cognitive impairment and subjective cognitive decline

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Alzheimer s & Dementia
Alzheimer's disease research and treatments
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Differences in plasmatic and CSF Alzheimer's Disease biomarkers considering ApoE genotype in mild cognitive impairment and subjective cognitive decline

Isadora Cristina Ribeiro, Brenda Costa Gonçalves, Marjorie Cristina Rocha da Silva, Ítalo Karmann Aventurato, Liara Rizzi, Gustavo Bruniera Peres Fernandes, Ananssa Silva, Thaís Lopes Pinheiro, Marcio Luiz Figueredo Balthazar, Luis E. Santos, Fernanda G. De Felice, Beatriz Ramos Lucente
article en

Abstract

Plasmatic AD biomarkers did not differ regarding APOE genotype in our sample, but we find a difference in CSF biomarker and the APOE genotype. So, our findings confirm the influence of APOE ε4 allele in central nervous system amyloid levels.

Alzheimer s & DementiaVol. 21(S2)
Universidade Estadual de Campinas (UNICAMP) (BR), Hospital Israelita Albert Einstein (BR), D’Or Institute for Research and Education (BR), Faculdade de Medicina de Jundiaí (BR)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
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