Resting state EEG Theta rhythms in healthy aging and Alzheimer's disease

Theta power and Theta rhythm duration are both linked to cognitive decline in MCI and AD but differ from healthy aging patterns. While Theta power reflects age-related changes, Theta rhythms duration may serve as a specific biomarker for disease progression in MCI and AD. These findings support the value of Rhythmicity analysis in EEG-based biomarkers of cognitive decline.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_103986
Primary Topic
EEG and Brain-Computer Interfaces
Type
article
Field-Weighted Citation Impact
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article

Resting state EEG Theta rhythms in healthy aging and Alzheimer's disease

Amir H. Meghdadi, Joanne M. Hamilton, Chris Berka, David H. Salat et al.
Alzheimer s & Dementia
EEG and Brain-Computer Interfaces
article

Resting state EEG Theta rhythms in healthy aging and Alzheimer's disease

Amir H. Meghdadi, Joanne M. Hamilton, Chris Berka, David H. Salat, Chenfei Ma, Erik K. St. Louis, Brad F Boeve, Ella J Thunen, Corinne E. Fischer
article en

Abstract

Theta power and Theta rhythm duration are both linked to cognitive decline in MCI and AD but differ from healthy aging patterns. While Theta power reflects age-related changes, Theta rhythms duration may serve as a specific biomarker for disease progression in MCI and AD. These findings support the value of Rhythmicity analysis in EEG-based biomarkers of cognitive decline.

Alzheimer s & DementiaVol. 21(S2)
St. Michael's Hospital (CA), Scripps Health (US), Harvard University (US), Massachusetts General Hospital (US), Mayo Clinic in Arizona (US), Advanced Brain Monitoring (United States) (US)
Openalex Percentile: Top 32%
EEG and Brain-Computer Interfaces
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