“Three of a kind?” Unmasking the clinical burden of human metapneumovirus and parainfluenza virus compared to respiratory syncytial virus in hospitalized adults: A pre-COVID-19 multicenter cohort study
RSV, PIV, and hMPV infections cause similar morbidity and mortality in hospitalized adults, yet PIV and hMPV remain markedly under-estimated causes of severe respiratory disease in this population. The unexpectedly better stability criteria observed with hMPV warrants further investigation. These findings highlight the importance of including hMPV and PIV in respiratory virus surveillance and future vaccine strategies.
Authors
- Christel Mamona
- Pierre de Truchis (ORCID: https://orcid.org/0000-0002-0038-2905)
- Sébastien Beaune (ORCID: https://orcid.org/0000-0001-9299-6703)
- Djillali Annane
- Elyanne Gault (ORCID: https://orcid.org/0000-0003-3855-9304)
- Benoit Lemarié
- Jennifer Dumoulin
- Azzam Saleh-Mghir
- Benjamin Davido
- Paul Loubet
Institutions
- Inserm (FR)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Université de Montpellier (FR)
- Université Paris-Saclay (FR)
- Hôpital Cochin (FR)
- Hôpital Ambroise-Paré (FR)
- Hôpital Raymond-Poincaré (FR)
- Université de Nîmes (FR)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1016/j.ijid.2025.108353
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 0.00