Association of baseline risk factors with subsequent cognitive decline in individuals with and without elevated brain amyloid enrolled in a preclinical AD treatment study

While common risk factors are associated with cognitive impairment regardless of amyloid status, some predictors and their presentations vary between Aβ+ and Aβ- individuals, suggesting distinct underlying mechanisms of cognitive decline.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_107735
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of baseline risk factors with subsequent cognitive decline in individuals with and without elevated brain amyloid enrolled in a preclinical AD treatment study

David L. Sultzer, Therese H Kim
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Association of baseline risk factors with subsequent cognitive decline in individuals with and without elevated brain amyloid enrolled in a preclinical AD treatment study

David L. Sultzer, Therese H Kim
article en

Abstract

While common risk factors are associated with cognitive impairment regardless of amyloid status, some predictors and their presentations vary between Aβ+ and Aβ- individuals, suggesting distinct underlying mechanisms of cognitive decline.

Alzheimer s & DementiaVol. 21(S3)
University of California, Irvine (US), UC Irvine Health (US)
Quality Education
Openalex Percentile: Top 32%
Dementia and Cognitive Impairment Research
DOIOpen Access PDFOpenAlex
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Association of baseline risk factors with subsequent cognitive decline in individuals with and without elevated brain amyloid enrolled in a preclinical AD treatment study — David L. Sultzer, Therese H Kim · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS