Early Cognitive Decline? Immediate Recall Deficits Predict Alzheimer's Progression

These findings highlight immediate consolidation deficits as a potential early marker of prodromal Alzheimer's disease, emphasizing their role in the preclinical trajectory of AD. The results suggest that immediate recall impairments, rather than delayed recall deficits, may better capture the earliest cognitive dysfunctions associated with disease progression. Incorporating short-term recall measures into clinical assessments could improve the early identification of high-risk individuals and refine predictive models for AD. Further research is needed to explore the underlying neural mechanisms linking immediate consolidation to Alzheimer's pathology.