Fitusiran: A Novel Antithrombin-Targeting Therapy for Hemophilia A and B, With or Without Inhibitors

Fitusiran expands prophylactic options for hemophilia A and B, providing sustained bleed protection with infrequent dosing. Integration into practice requires monitoring of antithrombin activity to mitigate thrombotic or bleeding risk, and liver and gallbladder functions for safety.

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Publication Details

Journal
Annals of Pharmacotherapy
Published
2025-12-26
DOI
https://doi.org/10.1177/10600280251403512
Primary Topic
Hemophilia Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Fitusiran: A Novel Antithrombin-Targeting Therapy for Hemophilia A and B, With or Without Inhibitors

Milap C. Nahata, Mohammad T. Alashqar
Annals of Pharmacotherapy
Hemophilia Treatment and Research
article

Fitusiran: A Novel Antithrombin-Targeting Therapy for Hemophilia A and B, With or Without Inhibitors

Milap C. Nahata, Mohammad T. Alashqar
article en

Abstract

Fitusiran expands prophylactic options for hemophilia A and B, providing sustained bleed protection with infrequent dosing. Integration into practice requires monitoring of antithrombin activity to mitigate thrombotic or bleeding risk, and liver and gallbladder functions for safety.

Annals of Pharmacotherapy
The Ohio State University (US)
Openalex Percentile: Top 25%
Hemophilia Treatment and Research
DOISourceOpenAlex
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Fitusiran: A Novel Antithrombin-Targeting Therapy for Hemophilia A and B, With or Without Inhibitors — Milap C. Nahata, Mohammad T. Alashqar · Annals of Pharmacotherapy (2025) | TGRS Research Map | TGRS