Assessment of Clinical Factors that Predict Response to Nabilone for Agitation in Alzheimer's Disease: A Post Hoc Analysis of a Randomized Control Trial

AD patients with pain, apathy and appetite changes, and with less cognitive impairment and not on ChEIs, were most likely to benefit from nabilone. If replicated with phase 3 data, these predictors may assist in guiding clinicians on who is likely to benefit from nabilone when managing agitation.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_103582
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessment of Clinical Factors that Predict Response to Nabilone for Agitation in Alzheimer's Disease: A Post Hoc Analysis of a Randomized Control Trial

Yejin Kang, Alex Kiss, Hui Jue Wang, Krista L. Lanctôt et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
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Assessment of Clinical Factors that Predict Response to Nabilone for Agitation in Alzheimer's Disease: A Post Hoc Analysis of a Randomized Control Trial

Yejin Kang, Alex Kiss, Hui Jue Wang, Krista L. Lanctôt, Giovanni Marotta, Oriel J. Feldman, Myuri Ruthirakuhan, Sandra E. Black, Damien Gallagher, Nathan Herrmann
article en

Abstract

AD patients with pain, apathy and appetite changes, and with less cognitive impairment and not on ChEIs, were most likely to benefit from nabilone. If replicated with phase 3 data, these predictors may assist in guiding clinicians on who is likely to benefit from nabilone when managing agitation.

Alzheimer s & DementiaVol. 21(S3)
Sunnybrook Health Science Centre (CA), University of Toronto (CA), Health Sciences Centre (CA), Ontario Brain Institute (CA), Sunnybrook Hospital (CA), Sunnybrook Research Institute
Reduced inequalities
Openalex Percentile: Top 33%
Dementia and Cognitive Impairment Research
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