Development of a novel micro-CT based scoring system for the assessment of joint structure in a rat model of inflammatory knee osteoarthritis
The novel micro-CT-based 3D imaging scoring system provides a reliable method for quantifying gross degenerative changes in rat knee joints in the MIA-induced OA model. While it does not directly assess cartilage, its correlation with histological findings suggests its utility as a complementary tool for evaluating overall joint degeneration.
Authors
- Young-Chang Park Arai (ORCID: https://orcid.org/0000-0002-2689-866X)
- Tatsunori Ikemoto (ORCID: https://orcid.org/0000-0002-4521-7639)
- Yusuke Ohmichi (ORCID: https://orcid.org/0000-0002-9503-8022)
- Mika Ohmichi
- Takuya Takata
- Kohei Hashimoto
- Nobunori Takahashi
- Masaki Nakano
Institutions
- Aichi Medical University (JP)
- Kanazawa Medical University (JP)
Publication Details
- Journal
- Annals of Translational Medicine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.21037/atm-25-101
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00