Lifetime risk of solid tumors and leukemia in Down Syndrome: a population-based Swedish matched cohort study

We present the most comprehensive profile of cancer risk in Down syndrome, aiming to guide clinical practices, encourage tailored surveillance recommendations, and incite research on chromosome 21's role in oncogenesis.

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Publication Details

Journal
British Journal of Cancer
Published
2025-12-26
DOI
https://doi.org/10.1038/s41416-025-03318-5
Primary Topic
Down syndrome and intellectual disability research
Type
article
Field-Weighted Citation Impact
0.00
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article

Lifetime risk of solid tumors and leukemia in Down Syndrome: a population-based Swedish matched cohort study

Benedicte Bang, Alexandra Wachtmeister, Anna Skarin Nordenvall, Giorgio Tettamanti et al.
British Journal of Cancer
Down syndrome and intellectual disability research
article

Lifetime risk of solid tumors and leukemia in Down Syndrome: a population-based Swedish matched cohort study

Benedicte Bang, Alexandra Wachtmeister, Anna Skarin Nordenvall, Giorgio Tettamanti, Bertil Johansson, Anna Martling, I. Nordgren, Y. Lu, Ann Nordgren
article en

Abstract

We present the most comprehensive profile of cancer risk in Down syndrome, aiming to guide clinical practices, encourage tailored surveillance recommendations, and incite research on chromosome 21's role in oncogenesis.

British Journal of CancerVol. 134(5)
Karolinska University Hospital (SE), Sahlgrenska University Hospital (SE), Karolinska Institutet (SE), Centre de recherche en Epidémiologie et Santé des Populations (FR), Skåne University Hospital (SE)
Good health and well-being
Openalex Percentile: Top 26%
Down syndrome and intellectual disability research
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Lifetime risk of solid tumors and leukemia in Down Syndrome: a population-based Swedish matched cohort study — Benedicte Bang, Alexandra Wachtmeister, et al. · British Journal of Cancer (2025) | TGRS Research Map | TGRS