A Numerical Study for Optimizing a New Experimental Method on Inhalation Toxicology

In this study, a new experimental method is proposed to evaluate the interaction between psychological state and behavioral changes under fire conditions. The ISO 5660-1 and the OFM (Open Field Maze) were employed to measure combustion characteristics and behavioral responses, respectively. Additional structure components were designed to establish appropriate inhalation environments with controlled temperature and uniform gas concentration within the OFM. A numerical simulation was then conducted to optimize these structural components for each inhalation method. The results confirmed that the proposed structures effectively provided proper thermal conditions and consistent gas concentrations inside the OFM. Therefore, the proposed experimental method improves the practicality and reliability of inhalation toxicology experiments. However, further research is required to enhance gas dispersion and to reduce excessive thermal effects under different inhalation conditions.