Bio-Molecular Cryptography for Protecting Nano-Network Transmissions in Healthcare Applications

Nano-technologies and communications at the nanoscale emerged as new approaches for data collection in many application domains, such as bio-medicine, healthcare, industry, agro-food, and military/defense. They usually entail a huge amount of continuous and real-time information to be processed from nano-devices, thus paving the way for the spreading of an innovation paradigm, represented by the Internet of Nano-Things (IoNT). The reliability of the envisioned IoNT applications still represents an open issue, due to the complexity of protecting the transmitted data at the nano-scale. In this context, this work proposes to adopt bio-molecular cryptography to secure data exchanges among the nano-devices in a nano-network, which integrates both molecular diffusion and electromagneticbased communication protocols. Bio-molecular cryptography is essentially based on the properties of DNA and proteins. Starting from such premises, a cryptographic algorithm is developed and its performance is evaluated on a reference IoNT scenario in the healthcare domain, along with the study of the behavior of different routing algorithms.

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Published
2025-12-01
DOI
https://doi.org/10.1109/wd67713.2025.11302720
Primary Topic
Molecular Communication and Nanonetworks
Type
article
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article

Bio-Molecular Cryptography for Protecting Nano-Network Transmissions in Healthcare Applications

Sabrina Sicari, Luigi Alfredo Grieco, Giuseppe Piro, Alessandra Rizzardi et al.
Molecular Communication and Nanonetworks
article

Bio-Molecular Cryptography for Protecting Nano-Network Transmissions in Healthcare Applications

Sabrina Sicari, Luigi Alfredo Grieco, Giuseppe Piro, Alessandra Rizzardi, Alberto Coen-Porisini
article en

Abstract

Nano-technologies and communications at the nanoscale emerged as new approaches for data collection in many application domains, such as bio-medicine, healthcare, industry, agro-food, and military/defense. They usually entail a huge amount of continuous and real-time information to be processed from nano-devices, thus paving the way for the spreading of an innovation paradigm, represented by the Internet of Nano-Things (IoNT). The reliability of the envisioned IoNT applications still represents an open issue, due to the complexity of protecting the transmitted data at the nano-scale. In this context, this work proposes to adopt bio-molecular cryptography to secure data exchanges among the nano-devices in a nano-network, which integrates both molecular diffusion and electromagneticbased communication protocols. Bio-molecular cryptography is essentially based on the properties of DNA and proteins. Starting from such premises, a cryptographic algorithm is developed and its performance is evaluated on a reference IoNT scenario in the healthcare domain, along with the study of the behavior of different routing algorithms.

University of Insubria (IT), Polytechnic University of Bari (IT)
Industry, innovation and infrastructure
Openalex Percentile: Top 42%
Molecular Communication and Nanonetworks
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Bio-Molecular Cryptography for Protecting Nano-Network Transmissions in Healthcare Applications — Sabrina Sicari, Luigi Alfredo Grieco, et al. · (2025) | TGRS Research Map | TGRS