Real-World Experience of Guselkumab in the Elderly Population

Guselkumab is effective and well tolerated in older adults with psoriasis. Baseline ELR, early PASI response, and chronic use of beta-blockers or aspirin may influence long-term treatment outcomes. While limited by the small sample size (66 patients), our findings represent the longest real-world follow-up to date among older psoriatic patients treated with guselkumab and support its use as a valuable therapeutic option in this population.

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Publication Details

Journal
Psoriasis Targets and Therapy
Published
2025-12-01
DOI
https://doi.org/10.2147/ptt.s549502
Citations
1
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.80
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article

Real-World Experience of Guselkumab in the Elderly Population

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1 citations
Psoriasis Targets and Therapy
Psoriasis: Treatment and Pathogenesis
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article

Real-World Experience of Guselkumab in the Elderly Population

Enrico Zelin, Vanessa Mazzoletti, Enzo Errichetti, Zeno Fratton, Vincenzo Maione, Stefano Bighetti, Giuseppe Stinco, Luca Bettolini, M. Venturini, Mariateresa Rossi
article en
1 citations

Abstract

Guselkumab is effective and well tolerated in older adults with psoriasis. Baseline ELR, early PASI response, and chronic use of beta-blockers or aspirin may influence long-term treatment outcomes. While limited by the small sample size (66 patients), our findings represent the longest real-world follow-up to date among older psoriatic patients treated with guselkumab and support its use as a valuable therapeutic option in this population.

Psoriasis Targets and TherapyVol. Volume 15
University of Udine (IT), Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT), Ospedale Santa Maria della Misericordia di Udine (IT), University of Brescia (IT)
Openalex Percentile: Top 20%
Psoriasis: Treatment and Pathogenesis
0.80
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Real-World Experience of Guselkumab in the Elderly Population — Enrico Zelin, Vanessa Mazzoletti, et al. · Psoriasis Targets and Therapy (2025) | TGRS Research Map | TGRS