Alzheimer’s disease molecular subtypes in a clinical trial cohort

The replication of the five AD molecular subtypes in an independent clinical trial cohort further supports the robustness of these subtypes and paves the way for personalized medicine and novel combination therapy approaches in AD. Reference 1. Tijms, B. M. et al. Cerebrospinal fluid proteomics in patients with Alzheimer's disease reveals five molecular subtypes with distinct genetic risk profiles. Nat. Aging 33-47 (2024) doi:10.1038/s43587-023-00550-7.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_105257
Primary Topic
Alzheimer's disease research and treatments
Type
article
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0.00
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article

Alzheimer’s disease molecular subtypes in a clinical trial cohort

Olav Mjaavatten, Frode S. Berven, Satya Saxena, Pallavi Sachdev et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Alzheimer’s disease molecular subtypes in a clinical trial cohort

Olav Mjaavatten, Frode S. Berven, Satya Saxena, Pallavi Sachdev, Charlotte E. Teunissen, Pieter Jelle Visser, Betty M. Tijms
article en

Abstract

The replication of the five AD molecular subtypes in an independent clinical trial cohort further supports the robustness of these subtypes and paves the way for personalized medicine and novel combination therapy approaches in AD. Reference 1. Tijms, B. M. et al. Cerebrospinal fluid proteomics in patients with Alzheimer's disease reveals five molecular subtypes with distinct genetic risk profiles. Nat. Aging 33-47 (2024) doi:10.1038/s43587-023-00550-7.

Alzheimer s & DementiaVol. 21(S5)
Eisai (United States) (US), Amsterdam University Medical Centers (NL), University of Bergen (NO), Vrije Universiteit Amsterdam (NL)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
DOIOpen Access PDFOpenAlex
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Alzheimer’s disease molecular subtypes in a clinical trial cohort — Olav Mjaavatten, Frode S. Berven, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS