Apremilast Alleviates Aβ Oligomer‐Induced Cytotoxicity via the PI3K/Akt Pathway

In conclusion, this study provides evidence that Apremilast can protect against AβOs-induced cytotoxicity in BV2 and HT-22 cells by modulating the PI3K/Akt signaling pathway, supporting its potential application in future clinical research.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_102959
Primary Topic
Phosphodiesterase function and regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

Apremilast Alleviates Aβ Oligomer‐Induced Cytotoxicity via the PI3K/Akt Pathway

Hu Yang
Alzheimer s & Dementia
Phosphodiesterase function and regulation
article

Apremilast Alleviates Aβ Oligomer‐Induced Cytotoxicity via the PI3K/Akt Pathway

Hu Yang
article en

Abstract

In conclusion, this study provides evidence that Apremilast can protect against AβOs-induced cytotoxicity in BV2 and HT-22 cells by modulating the PI3K/Akt signaling pathway, supporting its potential application in future clinical research.

Alzheimer s & DementiaVol. 21(S5)
Capital Medical University (CN)
Openalex Percentile: Top 36%
Phosphodiesterase function and regulation
DOIOpen Access PDFOpenAlex
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Apremilast Alleviates Aβ Oligomer‐Induced Cytotoxicity via the PI3K/Akt Pathway — Hu Yang · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS