The AD Biological Domains and Subdomains Expand the Multiomic Mapping into Data‐Driven Disease Endophenotypic Areas
The AD Biological Domains and subdomain development will facilitate future alignment of multiomic datasets onto a common open-source, open-science platform for integrative analysis and hypothesis generation. Data-driven standards for hypothesis generation may speed up the development of new therapeutic directions and drug target selection, opening new objective methods for translational advancement in AD.
Authors
- Karina Leal
- Jesse C. Wiley (ORCID: https://orcid.org/0000-0002-1430-772X)
- Gregory A. Cary (ORCID: https://orcid.org/0000-0003-3573-5229)
- William L. Poehlman (ORCID: https://orcid.org/0000-0002-3659-9663)
- Laura Heath (ORCID: https://orcid.org/0000-0002-0318-2773)
- Sruthi Ganesh
- Anna Greenwood
- Gregory W Carter
- Allan I. Levey
Institutions
- Sage Bionetworks (US)
- Emory University (US)
- Jackson Laboratory (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_103831
- Primary Topic
- Bioinformatics and Genomic Networks
- Type
- article
- Field-Weighted Citation Impact
- 0.00