Plasma Biomarker Characterization of Alzheimer’s Disease Psychosis in Study ACP‐204‐006

Biomarkers, rather than syndromic presentation, are recommended as a mechanism by which to define AD biologically. Since biomarker data from patients presenting with clinical symptoms consistent with Alzheimer's disease dementia and psychosis are sparse, we present biomarker data in a rigorously phenotyped population. These results can also inform the design and execution of clinical trials in ADP in the future.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_106556
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Plasma Biomarker Characterization of Alzheimer’s Disease Psychosis in Study ACP‐204‐006

Becky Howell, Bryan Dirks, Sanjeev Pathak, Samantha Friend et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Plasma Biomarker Characterization of Alzheimer’s Disease Psychosis in Study ACP‐204‐006

Becky Howell, Bryan Dirks, Sanjeev Pathak, Samantha Friend, Xiaoshu Feng, Peter M Zhang, Christine M Murphy
article en

Abstract

Biomarkers, rather than syndromic presentation, are recommended as a mechanism by which to define AD biologically. Since biomarker data from patients presenting with clinical symptoms consistent with Alzheimer's disease dementia and psychosis are sparse, we present biomarker data in a rigorously phenotyped population. These results can also inform the design and execution of clinical trials in ADP in the future.

Alzheimer s & DementiaVol. 21(S5)
Acadia Pharmaceuticals (United States) (US)
Partnerships for the goals
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
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