Enhanced feature dynamic fusion gated UNet for robust retinal vessel segmentation

This study proposes a Deep learning model, the Enhanced Feature Dynamic Fusion-Gated U-Net (EFDG-UNet), for retinal vessel segmentation. To address challenges in segmenting small vessels, handling lesion interference, and adapting to multi-scale structures, the model incorporates optimized feature fusion, dynamic selection, and global position modeling. The Feature Navigation Hub (FN-Hub) captures long-range dependencies across multiple encoder layers, improving multi-scale vessel segmentation. The Adaptive Gated Residual Block (AGRB) uses a dynamic gating mechanism to enhance feature selectivity in lesion areas and low-contrast scenarios. The Parallel Focused Attention Module (PFAM) optimizes channel and spatial information for fine-grained vessel features. Experimental validation on DRIVE, CHASE_DB1, and STARE datasets shows that EFDG-UNet achieves state-of-the-art performance, attaining an AUC of 0.9932 and F1-score of 0.8469 on CHASE_DB1, and an AUC of 0.9886 and F1-score of 0.8412 on DRIVE. The model shows improved performance in low-contrast regions and complex vessel structures compared to baseline methods.

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Publication Details

Journal
Scientific Reports
Published
2025-12-26
DOI
https://doi.org/10.1038/s41598-025-33694-0
Primary Topic
Retinal Imaging and Analysis
Type
article
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article

Enhanced feature dynamic fusion gated UNet for robust retinal vessel segmentation

Yifeng Li, Haibo Zhou, Tianyun Luan, Wanting Liu et al.
Scientific Reports
Retinal Imaging and Analysis
article

Enhanced feature dynamic fusion gated UNet for robust retinal vessel segmentation

Yifeng Li, Haibo Zhou, Tianyun Luan, Wanting Liu, Jikui Wang, Weihua Zhang, Xing Chen, Yang Yang, Dashi Ying
article en

Abstract

This study proposes a Deep learning model, the Enhanced Feature Dynamic Fusion-Gated U-Net (EFDG-UNet), for retinal vessel segmentation. To address challenges in segmenting small vessels, handling lesion interference, and adapting to multi-scale structures, the model incorporates optimized feature fusion, dynamic selection, and global position modeling. The Feature Navigation Hub (FN-Hub) captures long-range dependencies across multiple encoder layers, improving multi-scale vessel segmentation. The Adaptive Gated Residual Block (AGRB) uses a dynamic gating mechanism to enhance feature selectivity in lesion areas and low-contrast scenarios. The Parallel Focused Attention Module (PFAM) optimizes channel and spatial information for fine-grained vessel features. Experimental validation on DRIVE, CHASE_DB1, and STARE datasets shows that EFDG-UNet achieves state-of-the-art performance, attaining an AUC of 0.9932 and F1-score of 0.8469 on CHASE_DB1, and an AUC of 0.9886 and F1-score of 0.8412 on DRIVE. The model shows improved performance in low-contrast regions and complex vessel structures compared to baseline methods.

Scientific ReportsVol. 16(1)
Changchun University of Science and Technology (CN), Jilin Province Tumor Hospital (CN), Shanghai Customs College (CN), Jilin Agricultural Science and Technology University (CN), Chang Industry (United States) (US), First Bethune Hospital of Jilin University (CN), Changchun University (CN)
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Openalex Percentile: Top 31%
Retinal Imaging and Analysis
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