Enhanced feature dynamic fusion gated UNet for robust retinal vessel segmentation
This study proposes a Deep learning model, the Enhanced Feature Dynamic Fusion-Gated U-Net (EFDG-UNet), for retinal vessel segmentation. To address challenges in segmenting small vessels, handling lesion interference, and adapting to multi-scale structures, the model incorporates optimized feature fusion, dynamic selection, and global position modeling. The Feature Navigation Hub (FN-Hub) captures long-range dependencies across multiple encoder layers, improving multi-scale vessel segmentation. The Adaptive Gated Residual Block (AGRB) uses a dynamic gating mechanism to enhance feature selectivity in lesion areas and low-contrast scenarios. The Parallel Focused Attention Module (PFAM) optimizes channel and spatial information for fine-grained vessel features. Experimental validation on DRIVE, CHASE_DB1, and STARE datasets shows that EFDG-UNet achieves state-of-the-art performance, attaining an AUC of 0.9932 and F1-score of 0.8469 on CHASE_DB1, and an AUC of 0.9886 and F1-score of 0.8412 on DRIVE. The model shows improved performance in low-contrast regions and complex vessel structures compared to baseline methods.
Authors
- Yifeng Li (ORCID: https://orcid.org/0000-0001-8900-294X)
- Haibo Zhou (ORCID: https://orcid.org/0000-0002-2468-0093)
- Tianyun Luan
- Wanting Liu
- Jikui Wang
- Weihua Zhang
- Xing Chen
- Yang Yang
- Dashi Ying
Institutions
- Changchun University of Science and Technology (CN)
- Jilin Province Tumor Hospital (CN)
- Shanghai Customs College (CN)
- Jilin Agricultural Science and Technology University (CN)
- Chang Industry (United States) (US)
- First Bethune Hospital of Jilin University (CN)
- Changchun University (CN)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1038/s41598-025-33694-0
- Primary Topic
- Retinal Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00