A conditional two‐step approach for detecting Lewy Body pathology: smell function testing and α‐synuclein seed amplification
Implementing a two-step workflow in different clinical scenarios may reduce invasive testing with CSF, minimizing the burden for individuals and costs for healthcare providers.
Authors
- Piero Parchi (ORCID: https://orcid.org/0000-0002-9444-9524)
- Rik Ossenkoppele (ORCID: https://orcid.org/0000-0003-1584-7477)
- Sophie E Mastenbroek (ORCID: https://orcid.org/0009-0006-2759-9588)
- Jacob W. Vogel (ORCID: https://orcid.org/0000-0001-6394-9940)
- Oskar H. Hansson
- Claudia Marina Vargiu
- Frederik Barkhof
- Serena Caldera
- Sebastian Palmqvist
- Charles Adler
- Geidy E Serrano
- Lyduine E. Collij
- Thomas G Beach
Institutions
- Lund University (SE)
- Science for Life Laboratory (SE)
- AMN Healthcare (United States) (US)
- Amsterdam Neuroscience (NL)
- Istituto delle Scienze Neurologiche di Bologna (IT)
- Mayo Clinic in Arizona (US)
- Skåne University Hospital (SE)
- Banner Sun Health Research Institute (US)
- Amsterdam University Medical Centers (NL)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University College London (GB)
- Vrije Universiteit Amsterdam (NL)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
- University of Bologna (IT)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_102894
- Primary Topic
- Olfactory and Sensory Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00