Leveraging Vascular Over Ventricular Ratios in Observational Chronic Thromboembolic Pulmonary Hypertension and Acute Pulmonary Embolism Cohorts to Decode Clot Chronicity on Computed Tomography Angiography
This study evaluates the utility of CT-derived PA/A and RV/LV ratios in distinguishing surgically accessible CTEPH from acute PE and negative controls. Unlike the RV/LV ratio, PA/A ratio was significantly higher in CTEPH patients compared to low and intermediate/high-risk acute PE cohorts, indicating its utility as a marker of clot chronicity.
Authors
- Michael J. Cuttica (ORCID: https://orcid.org/0000-0002-0084-8760)
- Stephen F. Chiu (ORCID: https://orcid.org/0000-0003-2759-9394)
- Sarah Khorasani (ORCID: https://orcid.org/0000-0001-7190-032X)
- Daniel Schimmel (ORCID: https://orcid.org/0000-0001-6035-7317)
- Ruben Mylvaganam (ORCID: https://orcid.org/0000-0002-7203-7609)
- S. Laurenzo
- Jared D. Larson
- Farbod Rahaghi
- S. Christopher Malaisrie
Institutions
- Northwestern University (US)
- Brigham and Women's Hospital (US)
Publication Details
- Journal
- Pulmonary Circulation
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/pul2.70223
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00