High intensity focused ultrasound in small saphenous vein incompetence: a pilot feasibility study

BackgroundThis study explores the effectiveness of High Intensity Focused Ultrasound (HIFU) in treating incompetence of the small saphenous vein (SSV).Materials and methodsPatients diagnosed with SSV incompetence received HIFU treatment. The primary outcome measured was the rate of SSV competent shrinkage or closure after 1 year.ResultsAmong the 292 legs treated with HIFU for chronic venous disease, 15 (5.1%) were for SSV incompetence. Quality of life, assessed using the CIVIQ-20, showed a significant improvement at 3 months post-treatment, decreasing from 38.9 ± 9.1 to 24.3 ± 2.0 (p < .01). The rVCSS also improved, declining from 6.5 ± 1.7 to 5.0 ± 1.0, although this change was not statistically significant (p = ns). All SSVs were closed or competent with evidence of shrinkage at 1 week, 3 months, 6 months, and 1 year following HIFU. No recurrent varicose veins were identified during the follow-up period.ConclusionThese initial findings indicate that HIFU may be an effective option for addressing SSV incompetence. Additional studies are necessary to compare this method with other treatments and to evaluate long-term results with a more robust patient cohort.

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Publication Details

Journal
Phlebology The Journal of Venous Disease
Published
2025-12-26
DOI
https://doi.org/10.1177/02683555251413661
Primary Topic
Diagnosis and Treatment of Venous Diseases
Type
article
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article

High intensity focused ultrasound in small saphenous vein incompetence: a pilot feasibility study

Emanuele Nanni, Matteo Pizzamiglio, Paolo Casoni, Daniele Bissacco
Phlebology The Journal of Venous Disease
Diagnosis and Treatment of Venous Diseases
article

High intensity focused ultrasound in small saphenous vein incompetence: a pilot feasibility study

Emanuele Nanni, Matteo Pizzamiglio, Paolo Casoni, Daniele Bissacco
article en

Abstract

BackgroundThis study explores the effectiveness of High Intensity Focused Ultrasound (HIFU) in treating incompetence of the small saphenous vein (SSV).Materials and methodsPatients diagnosed with SSV incompetence received HIFU treatment. The primary outcome measured was the rate of SSV competent shrinkage or closure after 1 year.ResultsAmong the 292 legs treated with HIFU for chronic venous disease, 15 (5.1%) were for SSV incompetence. Quality of life, assessed using the CIVIQ-20, showed a significant improvement at 3 months post-treatment, decreasing from 38.9 ± 9.1 to 24.3 ± 2.0 (p < .01). The rVCSS also improved, declining from 6.5 ± 1.7 to 5.0 ± 1.0, although this change was not statistically significant (p = ns). All SSVs were closed or competent with evidence of shrinkage at 1 week, 3 months, 6 months, and 1 year following HIFU. No recurrent varicose veins were identified during the follow-up period.ConclusionThese initial findings indicate that HIFU may be an effective option for addressing SSV incompetence. Additional studies are necessary to compare this method with other treatments and to evaluate long-term results with a more robust patient cohort.

Phlebology The Journal of Venous Disease
Cleveland Clinic (US), University of Milan (IT)
Openalex Percentile: Top 26%
Diagnosis and Treatment of Venous Diseases
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