Metabolic Dysregulation in Alzheimer's Disease: A High‐Resolution Brain Metabolomics Approach
This study demonstrates the potential of high-resolution metabolomic profiling in brain tissues to elucidate molecular mechanisms underlying AD pathology. Our findings provide critical insights into metabolic dysregulation in AD and its interplay with genetic factors. Future longitudinal studies are needed to validate these findings and explore the functional significance of the identified metabolites in AD progression.
Authors
- Emma Casey (ORCID: https://orcid.org/0009-0006-4303-4755)
- Youran Tan (ORCID: https://orcid.org/0000-0002-9955-8324)
- Donghai Liang (ORCID: https://orcid.org/0000-0001-7311-2298)
- Aliza P. Wingo (ORCID: https://orcid.org/0000-0002-6360-6726)
- Zhenjiang Li (ORCID: https://orcid.org/0000-0002-4806-6231)
- D. Benson Walker
- Thomas S. Wingo (ORCID: https://orcid.org/0000-0002-7679-6282)
- Anke Huels
- Dean P Jones
- Marla Gearing
- James J. Lah
- Allan I. Levey
Institutions
- Emory University (US)
- University of California, Davis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_104496
- Citations
- 1
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.81