Iatrogenic atrial septal defect following transcatheter edge-to-edge mitral valve repair: A systematic review and meta-analysis

This systematic review and meta-analysis identified several related predictors of iASD persistence, possibly leading to right heart volume overload and a higher risk of heart failure rehospitalization. In order to generalize our findings, larger clinical studies in independent patient cohorts are necessary. What's more, there is a need to perform a careful decision for interventional closure of an iASD after TEER.