Blood‐based Biomarkers for Alzheimer's Disease and Memory Function in Midlife

Although AD biomarker levels have been found to correlate with memory functioning in older adult samples, we did not observe these same effects in middle adulthood. Thus, the current results suggest that individual differences in blood-based AD biomarkers may not have predictive utility for observed memory functioning in middle adulthood.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_104460
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Blood‐based Biomarkers for Alzheimer's Disease and Memory Function in Midlife

Alyssa Kam, Christopher R. Beam, Deborah Winders Davis, Sophie A. Bell et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Blood‐based Biomarkers for Alzheimer's Disease and Memory Function in Midlife

Alyssa Kam, Christopher R. Beam, Deborah Winders Davis, Sophie A. Bell, Ebrahim Zandi, Eric Turkheimer, Deborah Finkel, Bruna Martins‐Klein
article en

Abstract

Although AD biomarker levels have been found to correlate with memory functioning in older adult samples, we did not observe these same effects in middle adulthood. Thus, the current results suggest that individual differences in blood-based AD biomarkers may not have predictive utility for observed memory functioning in middle adulthood.

Alzheimer s & DementiaVol. 21(S3)
University of Southern California (US), University of Louisville (US), Norton Healthcare (US), University of Virginia (US), Jönköping University (SE)
No poverty
Openalex Percentile: Top 33%
Dementia and Cognitive Impairment Research
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Blood‐based Biomarkers for Alzheimer's Disease and Memory Function in Midlife — Alyssa Kam, Christopher R. Beam, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS