Aspirin plus clopidogrel versus aspirin alone in patients with mild-to-moderate stroke: A systematic review and meta-analysis
DAPT demonstrated a non-significant trend toward reduced risk of END and recurrent ischemic stroke without increasing the risk of bleeding events compared to aspirin monotherapy in patients with mild to moderate stroke. Further large-scale trials are needed to confirm these potential benefits.
Authors
- Areeba Ahsan (ORCID: https://orcid.org/0009-0005-8209-3283)
- Zain Ali Nadeem (ORCID: https://orcid.org/0009-0008-5968-4538)
- Rukesh Yadav (ORCID: https://orcid.org/0000-0002-0282-0251)
- Shrey Gole (ORCID: https://orcid.org/0000-0002-1015-4201)
- Laveeza Fatima (ORCID: https://orcid.org/0000-0002-4152-8202)
- Rubab Zahra (ORCID: https://orcid.org/0009-0006-9624-3200)
- Mushood Ahmed (ORCID: https://orcid.org/0000-0001-9872-8224)
- H Jain
- Muhammed Ameen Noushad
- Eeshal Fatima
- Tallal Mushtaq Hashmi
- Lilia Megherbi
- Raheel Ahmed
- Kamleshun Ramphul
Institutions
- Services Institute of Medical Sciences (PK)
- Rawalpindi Medical University (PK)
- Allama Iqbal Medical College (PK)
- All India Institute of Medical Sciences Jodhpur (IN)
- Royal Brompton Hospital (GB)
- Tribhuvan University Teaching Hospital (NP)
- University Hospitals Plymouth NHS Trust (GB)
- Imperial College London (GB)
- Stanford University (US)
Publication Details
- Journal
- Medicine
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1097/md.0000000000046821
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00