Therapeutic Efficacy of Xanomeline on Psychotropic Drug‐Induced Cognitive Dysfunction in Rats
The findings suggest a functional interaction between the muscarinic cholinergic and dopaminergic/NMDA systems in modulating recognition memory. Muscarinic cholinergic agonists, such as xanomeline, may hold therapeutic potential for treating cognitive impairments associated with psychotropic drug abuse.
Authors
- Cheng Peng (ORCID: https://orcid.org/0009-0006-9014-6653)
- Zonghao Yu
- Lifeng Zhang
- Juan Tan
Institutions
- WuXi AppTec (China) (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_100720
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00