Tablet‐based cognitive assessment in a multisite study of early‐onset AD: association with pen‐and‐paper tests and PET measures of amyloid and tau
In this large multisite study, TabCAT measures show good concurrent validity and associations with pathophysiological markers of AD: Aβ-PET positivity and neuroanatomical specific patterns of tau-PET. These digital measures have promise for frontline identification and early diagnosis of patients with EOAD.
Authors
- Konstantinos Chiotis (ORCID: https://orcid.org/0000-0002-5679-0297)
- Ranjani Shankar
- Renaud La Joie (ORCID: https://orcid.org/0000-0003-2581-8100)
- Salma Rocha
- Dustin B. Hammers (ORCID: https://orcid.org/0000-0002-1644-2618)
- Isabel Elaine Allen (ORCID: https://orcid.org/0000-0001-9029-9744)
- Ganna Blazhenets (ORCID: https://orcid.org/0000-0003-2419-7373)
- Ani Eloyan (ORCID: https://orcid.org/0000-0002-8110-7680)
- Katherine L. Possin (ORCID: https://orcid.org/0000-0002-6623-3793)
- Alinda Amuiri
- Piyush Maiti
- Kala Kirby
- Elena Tsoy
- Brad C. Dickerson
- Liana G. Apostolova
- Robert A. Koeppe
- Maria C. Carrillo
- Gil D. Rabinovici
- W. Yembe Njamnshi
Institutions
- Alzheimer's Association (US)
- Harvard University (US)
- University of California, San Francisco (US)
- Brown University (US)
- University of Michigan (US)
- Massachusetts General Hospital (US)
- University Memory and Aging Center (US)
- University Teaching Hospital of Yaounde (CM)
- Global Brain Health Institute (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_104654
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00