Cognitive Profiles in Alzheimer's Disease: Insights from a Multicenter Study in Peru

These findings confirm the severe cognitive and executive impairments in AD patients compared to MCI and controls. The significant differences in RUDAS and INECO scores highlight their potential role in differentiating neurocognitive conditions. Impairments in control inhibitory functions and working memory were evident in AD patients. This study provides novel insights into dementia evaluation in Peru and underscores the importance of standardized neuropsychological assessments for early identification of cognitive decline. Future research should expand sample sizes and refine assessment tools to improve early detection strategies.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_107776
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Cognitive Profiles in Alzheimer's Disease: Insights from a Multicenter Study in Peru

Brenda Nadia Chino Vilca, Jose Carreño‐Galvez, Harold Alessandro Arana‐Nombera, Leandro Aron Perez‐Fernandez et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Cognitive Profiles in Alzheimer's Disease: Insights from a Multicenter Study in Peru

Brenda Nadia Chino Vilca, Jose Carreño‐Galvez, Harold Alessandro Arana‐Nombera, Leandro Aron Perez‐Fernandez, Reyna Elizabeth Alamo‐Medina, Viviana Nayelli Gallegos‐Manayay, María del Rosario Oliva‐Piscoya, María Celinda Cruz Ordinola, Milagros del Rocio Casimiro‐Arana, Leslie Magdalena Lozada Tantarico, José Cabrejo, Sheila Castro‐Suarez, Jonathan Adrian Zegarra‐Valdivia, Carmen Paredes Manrique, Diana Gutierrez‐Flores, Emily Gonzales‐Manayalle, Gilda Flores‐Valdivia, César Ramal‐Ansayac, Ernesto Gabriel Adolfo‐Espinoza, Noelia Graciela Raffo‐Moron, Nilton Custodio
article en

Abstract

These findings confirm the severe cognitive and executive impairments in AD patients compared to MCI and controls. The significant differences in RUDAS and INECO scores highlight their potential role in differentiating neurocognitive conditions. Impairments in control inhibitory functions and working memory were evident in AD patients. This study provides novel insights into dementia evaluation in Peru and underscores the importance of standardized neuropsychological assessments for early identification of cognitive decline. Future research should expand sample sizes and refine assessment tools to improve early detection strategies.

Alzheimer s & DementiaVol. 21(S3)
Universidad de San Martín de Porres (PE), Universidad Nacional de San Agustin de Arequipa (PE), Achucarro Basque Center for Neuroscience (ES), Catholic University of Santa María (PE), Instituto Nacional de Enfermedades Neoplásicas (PE), Forum Solidaridad Perú (PE), Universidad Particular de Iquitos (PE), Institute of Peruvian Studies (PE), Universidad Católica San Pablo (PE), Universidad Peruana Unión (PE), Universidad Tecnológica del Perú (PE), Ministry of Health (PE), Universidad de Lambayeque (PE), Global Brain Health Institute (US), Universidad Continental (PE), Universidad Señor de Sipán (PE), Instituto Nacional de Ciencias Neurológicas
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Dementia and Cognitive Impairment Research
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