Dapagliflozin enhances gut barrier function in rats with chronic myocardial infarction by modulating gut microbiota balance

In this CMI rat model, dapagliflozin was associated with changes in the gut-heart axis that may relate to its observed cardioprotective effects. Further studies are required to determine causality and the relative contribution of these pathways.

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Publication Details

Journal
Annals of Translational Medicine
Published
2025-12-01
DOI
https://doi.org/10.21037/atm-25-132
Citations
1
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.81
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article

Dapagliflozin enhances gut barrier function in rats with chronic myocardial infarction by modulating gut microbiota balance

Chayodom Maneechote, Chitlada Parbao, Chanon Kunasol, Wichwara Nawara et al.
1 citations
Annals of Translational Medicine
Gut microbiota and health
0.81
article

Dapagliflozin enhances gut barrier function in rats with chronic myocardial infarction by modulating gut microbiota balance

Chayodom Maneechote, Chitlada Parbao, Chanon Kunasol, Wichwara Nawara, Nipon Chattipakorn, Chanisa Thonusin, Nattayaporn Apaijai, Siriporn C. Chattipakorn
article en
1 citations

Abstract

In this CMI rat model, dapagliflozin was associated with changes in the gut-heart axis that may relate to its observed cardioprotective effects. Further studies are required to determine causality and the relative contribution of these pathways.

Annals of Translational MedicineVol. 13(6)
The Royal College Of Anesthesiologists Of Thailand (TH), Office of the Royal Society, Chiang Mai University (TH)
Good health and well-being
Openalex Percentile: Top 20%
Gut microbiota and health
0.81
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