The role of tau and amyloid pathology in neurosensory impairments during preclinical Alzheimer's disease
Our analyses suggest that the presence of pathological amyloid and tau (A+T+) is associated with declines in the neurosensory domain of odor identification. Future studies should examine whether similar trends are observed for other neurosensory domains such as vision and gustation.
Authors
- Fernando González‐Ortiz (ORCID: https://orcid.org/0000-0001-7897-9456)
- Daniel C. Bowie (ORCID: https://orcid.org/0000-0002-7024-2318)
- Valentin Ourry (ORCID: https://orcid.org/0000-0002-8535-9009)
- Yara Yakoub (ORCID: https://orcid.org/0000-0002-4769-7162)
- Kaj Blennow
- Sylvia Villeneuve (ORCID: https://orcid.org/0000-0003-2338-0467)
- Josée Poirier (ORCID: https://orcid.org/0000-0002-1302-869X)
- Ting Qiu (ORCID: https://orcid.org/0009-0007-8209-4424)
- Henrik Zetterberg
Institutions
- Douglas Mental Health University Institute (CA)
- Sahlgrenska University Hospital (SE)
- University College London (GB)
- McGill University (CA)
- University of Gothenburg (SE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_104086
- Primary Topic
- Olfactory and Sensory Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00