Chronicity and physical activity levels independently associate with spatial patterns of multifidus fat infiltration in chronic low back pain patients
Increased cLBP chronicity and lower physical activity levels independently associate with elevated MF FI. Further, these associations are independent of age, disc degeneration, and pain severity. Lastly, physical activity may have an independent association with MF FI specific to the deep MF, where fat infiltration has been shown to associate with cLBP symptoms and adjacent disc degeneration.
Authors
- Aaron J. Fields (ORCID: https://orcid.org/0000-0001-6460-4506)
- Jeannie F. Bailey (ORCID: https://orcid.org/0000-0003-4618-7512)
- Lucas Dziesinski (ORCID: https://orcid.org/0000-0002-0192-5879)
- Jiamin Zhou (ORCID: https://orcid.org/0000-0002-9224-2060)
- Conor W. O’Neill
- Karim Khattab
- Jeffrey C. Lotz
Institutions
- University of California, San Francisco (US)
Publication Details
- Journal
- European Spine Journal
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1007/s00586-025-09660-9
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- University of California, Davis
- University of California, San Francisco
- National Institute of Arthritis and Musculoskeletal and Skin Diseases