Paraganglioma of the urinary bladder: A case report and discussion of the literature

Urinary bladder paragangliomas (UBPGL) are rare neuroendocrine tumors that originate from extra-adrenal paraganglia in the bladder. We report the case of a 67-year-old patient who presented with a submucosal bladder tumor. A hypertensive crisis developed during the initial attempt at cystoscopic resection, and biopsies demonstrated a UBPGL. The importance of considering UBPGL in the differential diagnosis of submucosal bladder tumors is discussed. Appropriate perioperative blood pressure management and the choice of surgical approach can optimize outcomes and prevent morbidity.

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Publication Details

Journal
Urology Case Reports
Published
2025-12-26
DOI
https://doi.org/10.1016/j.eucr.2025.103327
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
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article

Paraganglioma of the urinary bladder: A case report and discussion of the literature

Carlos A. Puyo, Robert A. Edelstein, Samuel S Iofel, Lija Mary Kambakkaran Joseph et al.
Urology Case Reports
Adrenal and Paraganglionic Tumors
article

Paraganglioma of the urinary bladder: A case report and discussion of the literature

Carlos A. Puyo, Robert A. Edelstein, Samuel S Iofel, Lija Mary Kambakkaran Joseph, Daniel Groves
article en

Abstract

Urinary bladder paragangliomas (UBPGL) are rare neuroendocrine tumors that originate from extra-adrenal paraganglia in the bladder. We report the case of a 67-year-old patient who presented with a submucosal bladder tumor. A hypertensive crisis developed during the initial attempt at cystoscopic resection, and biopsies demonstrated a UBPGL. The importance of considering UBPGL in the differential diagnosis of submucosal bladder tumors is discussed. Appropriate perioperative blood pressure management and the choice of surgical approach can optimize outcomes and prevent morbidity.

Urology Case ReportsVol. 65
Tufts University (US), Lowell General Hospital (US)
Good health and well-being
Openalex Percentile: Top 26%
Adrenal and Paraganglionic Tumors
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