Time in Tight Range Versus Time in Range for Predicting Diabetic Retinopathy in Adults with Type 1 Diabetes Using Multiple Daily Insulin Injections: A Retrospective Longitudinal Study with isCGM Data
TITR provides modestly superior predictive value over TIR for incident DR, particularly in individuals with near-target HbA1c, but both metrics perform similarly for predicting progression. CGM-derived metrics should be interpreted in the context of overall glycemic control and clinical risk factors.
Authors
- José Alfonso Arranz Martín (ORCID: https://orcid.org/0000-0002-0140-1522)
- Víctor Navas-Moreno (ORCID: https://orcid.org/0009-0001-8138-4178)
- Selma Amar
- Sara González Castañar
- Alberto Santiago-Redondo
- Elena García-Artacho
- Eduardo Pedro López Palacios
- Fernando Sebastian-Valles
- Maria Sara Tapia-Sanchiz
- Mónica Marazuela
Institutions
- Hospital Universitario de La Princesa (ES)
- Universidad Autónoma de Madrid (ES)
Publication Details
- Journal
- Diabetes Technology & Therapeutics
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1177/15209156251403567
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00