Increased risk of mild cognitive impairment is associated with severe periodontitis: A cross‐sectional study

This study looked at whether middle-aged people with severe gum disease (periodontitis) are more likely to have problems with thinking and memory. Researchers worked with 102 patients, some with severe gum disease and others with milder forms. Each participant had their teeth and gums examined and completed tests that measured memory, attention span, and how quickly they could think and react. The results showed that those with more severe gum disease tended to have worse results on a key test, suggesting a link between gum health and brain function. In fact, people with severe gum disease had a higher chance of displaying symptoms of mild cognitive impairment, a condition that can lead to memory loss and dementia over time. These findings suggest that keeping gums healthy may be important not just for oral health, but also for protecting brain health as we age.

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Publication Details

Journal
Journal of Periodontology
Published
2025-12-26
DOI
https://doi.org/10.1002/jper.70042
Primary Topic
Oral microbiology and periodontitis research
Type
article
Field-Weighted Citation Impact
0.00
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article

Increased risk of mild cognitive impairment is associated with severe periodontitis: A cross‐sectional study

Ivana Milardović, A. Sculean, Marija Roguljić, Ivica Bilić et al.
Journal of Periodontology
Oral microbiology and periodontitis research
article

Increased risk of mild cognitive impairment is associated with severe periodontitis: A cross‐sectional study

Ivana Milardović, A. Sculean, Marija Roguljić, Ivica Bilić, Ana Družijanić, Ana Kostović, Lea Starman
article en

Abstract

This study looked at whether middle-aged people with severe gum disease (periodontitis) are more likely to have problems with thinking and memory. Researchers worked with 102 patients, some with severe gum disease and others with milder forms. Each participant had their teeth and gums examined and completed tests that measured memory, attention span, and how quickly they could think and react. The results showed that those with more severe gum disease tended to have worse results on a key test, suggesting a link between gum health and brain function. In fact, people with severe gum disease had a higher chance of displaying symptoms of mild cognitive impairment, a condition that can lead to memory loss and dementia over time. These findings suggest that keeping gums healthy may be important not just for oral health, but also for protecting brain health as we age.

Journal of Periodontology
University of Bern (CH), University of Split (HR)
Openalex Percentile: Top 32%
Oral microbiology and periodontitis research
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