Sex differences in structural connectivity‐based AD pathology in the Indiana Memory and Aging cohort

Current literature supports the key role that both the accumbens (Guo et al., 2022) and temporopolar regions (Dautricourt et al., 2021) play in AD. We found differences between males and females in their structural connectivity-based AD pathology, with women showing the left accumbens and right temporopolar regions consistently impacted by the development of MCI.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_103077
Primary Topic
Advanced Neuroimaging Techniques and Applications
Type
article
Field-Weighted Citation Impact
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article

Sex differences in structural connectivity‐based AD pathology in the Indiana Memory and Aging cohort

Selena Wang, Qiuting Wen, Plamena P. Powla, Yu‐Chien Wu et al.
Alzheimer s & Dementia
Advanced Neuroimaging Techniques and Applications
article

Sex differences in structural connectivity‐based AD pathology in the Indiana Memory and Aging cohort

Selena Wang, Qiuting Wen, Plamena P. Powla, Yu‐Chien Wu, Andrew Joel Saykin, Connor Lee Cornelison, Theyaneshwaran Jayaprakash, Shannon L Risacher
article en

Abstract

Current literature supports the key role that both the accumbens (Guo et al., 2022) and temporopolar regions (Dautricourt et al., 2021) play in AD. We found differences between males and females in their structural connectivity-based AD pathology, with women showing the left accumbens and right temporopolar regions consistently impacted by the development of MCI.

Alzheimer s & DementiaVol. 21(S2)
Indiana University Bloomington (US), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US)
Gender equality
Openalex Percentile: Top 31%
Advanced Neuroimaging Techniques and Applications
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