Associations of subjective cognitive decline with MRI biomarkers of neurodegeneration and vascular injury and amyloid PET in an ethnoracially diverse cohort

In this diverse cohort of older adults, greater subjective cognitive decline was associated with worse late-life brain health. These findings highlight the importance of addressing subjective cognitive decline as potential indicators of neurodegeneration, cerebrovascular injury, and amyloid burden.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_105950
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Associations of subjective cognitive decline with MRI biomarkers of neurodegeneration and vascular injury and amyloid PET in an ethnoracially diverse cohort

Alexander Ivan B. Posis, Nancy X Chen, Sarah Farias, Batool Rizvi et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Associations of subjective cognitive decline with MRI biomarkers of neurodegeneration and vascular injury and amyloid PET in an ethnoracially diverse cohort

Alexander Ivan B. Posis, Nancy X Chen, Sarah Farias, Batool Rizvi, Elizabeth Rose Mayeda, M. Maria Glymour, María M. M. Corrada, Rachel A. Whitmer, Paola Gilsanz
article en

Abstract

In this diverse cohort of older adults, greater subjective cognitive decline was associated with worse late-life brain health. These findings highlight the importance of addressing subjective cognitive decline as potential indicators of neurodegeneration, cerebrovascular injury, and amyloid burden.

Alzheimer s & DementiaVol. 21(S3)
Boston University (US), Kaiser Permanente (US), University of California, Los Angeles (US), University of California, Irvine (US), Fielding Graduate University (US), University of California, Davis (US)
Openalex Percentile: Top 33%
Dementia and Cognitive Impairment Research
DOIOpen Access PDFOpenAlex
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Associations of subjective cognitive decline with MRI biomarkers of neurodegeneration and vascular injury and amyloid PET in an ethnoracially diverse cohort — Alexander Ivan B. Posis, Nancy X Chen, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS