Precision Medicine in Alzheimer’s Disease (AD): Observed Efficacy Treatment Effects from Blarcamesine Clinical AD Trials
Thus, the specificity of blarcamesine to this genotype underscores the importance of understanding clear MoA and potential for further improved personalized medicine in AD treatment, as therapies targeting individual molecular profiles could achieve more substantial and sustained benefits. While Precision Medicine holds great promise for improving the treatment paradigm of AD by offering more personalized, likely more effective therapies, it also introduces challenges related to potential cost, data privacy, ethical concerns, and inequities in access. Addressing these issues is crucial to ensure that the benefits of Precision Medicine can be realized for all patients.
Authors
- Kun Jin (ORCID: https://orcid.org/0000-0002-8208-7052)
- Christopher U. Missling
- Nicolas Guizard (ORCID: https://orcid.org/0000-0003-2660-5123)
- William R Chezem (ORCID: https://orcid.org/0000-0002-8939-758X)
- Olivier Courrèges
- Luca Villa
- Ayoub Gueddou
- Elizabeth Gordon
- Mathilde Borrot
- Timo Grimmer
- Juan Carlos Lopez‐Talavera
- Marwan N. Sabbagh
- Audrey Gabelle
Institutions
- Barrow Neurological Institute (US)
- Enzo Life Sciences (United States) (US)
- Erdyn (France) (FR)
- Technical University of Munich (DE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_106527
- Primary Topic
- Pharmacological Receptor Mechanisms and Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00