Precision Medicine in Alzheimer’s Disease (AD): Observed Efficacy Treatment Effects from Blarcamesine Clinical AD Trials

Thus, the specificity of blarcamesine to this genotype underscores the importance of understanding clear MoA and potential for further improved personalized medicine in AD treatment, as therapies targeting individual molecular profiles could achieve more substantial and sustained benefits. While Precision Medicine holds great promise for improving the treatment paradigm of AD by offering more personalized, likely more effective therapies, it also introduces challenges related to potential cost, data privacy, ethical concerns, and inequities in access. Addressing these issues is crucial to ensure that the benefits of Precision Medicine can be realized for all patients.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_106527
Primary Topic
Pharmacological Receptor Mechanisms and Effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Precision Medicine in Alzheimer’s Disease (AD): Observed Efficacy Treatment Effects from Blarcamesine Clinical AD Trials

Kun Jin, Christopher U. Missling, Nicolas Guizard, William R Chezem et al.
Alzheimer s & Dementia
Pharmacological Receptor Mechanisms and Effects
article

Precision Medicine in Alzheimer’s Disease (AD): Observed Efficacy Treatment Effects from Blarcamesine Clinical AD Trials

Kun Jin, Christopher U. Missling, Nicolas Guizard, William R Chezem, Olivier Courrèges, Luca Villa, Ayoub Gueddou, Elizabeth Gordon, Mathilde Borrot, Timo Grimmer, Juan Carlos Lopez‐Talavera, Marwan N. Sabbagh, Audrey Gabelle
article en

Abstract

Thus, the specificity of blarcamesine to this genotype underscores the importance of understanding clear MoA and potential for further improved personalized medicine in AD treatment, as therapies targeting individual molecular profiles could achieve more substantial and sustained benefits. While Precision Medicine holds great promise for improving the treatment paradigm of AD by offering more personalized, likely more effective therapies, it also introduces challenges related to potential cost, data privacy, ethical concerns, and inequities in access. Addressing these issues is crucial to ensure that the benefits of Precision Medicine can be realized for all patients.

Alzheimer s & DementiaVol. 21(S5)
Barrow Neurological Institute (US), Enzo Life Sciences (United States) (US), Erdyn (France) (FR), Technical University of Munich (DE)
Openalex Percentile: Top 36%
Pharmacological Receptor Mechanisms and Effects
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